Glycol chitosan-based tacrolimus-loaded nanomicelle therapy ameliorates lupus nephritis
نویسندگان
چکیده
منابع مشابه
TAC-TIC use of tacrolimus-based regimens in lupus nephritis
Current guidelines do not mention tacrolimus (TAC) as a treatment option and no consensus has been reported on the role of TAC in lupus nephritis (LN). The present study aimed to guide clinical judgement on the use of TAC in patients with LN. A meta-analysis was performed for clinical studies investigating TAC regimens in LN on the basis of treatment target (induction or maintenance), concomita...
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The pharmacokinetics of orally administered tacrolimus were examined in six female lupus nephritis patients (mean age 43 years, range 24-55 years). Tacrolimus (3 mg) was administered after supper, and blood tacrolimus concentrations were measured just prior to dosing and 1, 2, 4, 6, 8, 12 and 24 h after administration. The maximum blood concentration (C(max)) was observed 4-8 h (mean: 6.7 h) af...
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ژورنال
عنوان ژورنال: Journal of Nanobiotechnology
سال: 2021
ISSN: 1477-3155
DOI: 10.1186/s12951-021-00857-w